Are You There, Chelsea? premieres Wednesday, Jan. 11th at 8:30 PM on NBC. Laura Prepon (That 70’s Show, October Road) portrays a 20s-something Chelsea Handler and Handler portrays her sister Sloane and is based on Handler’s three books My Horizontal Life: A Collection of One-Night Stands, Are You There Vodka? It’s Me Chelsea, and Chelsea Chelsea Bang Bang. Handler, who serves as executive producer on the show, and Prepon recently spoke with the media about the upcoming series.